Analysis:

• 1-hydroxy-pyrene in urine
• 5-Nitro-gamma tocopherol in plasma
• Ammonia in urine
• APO-A1 in plasma by AA
• Apo-B in plasma by AA
• Apo-E in plasma by AA
• Betaine and choline in plasma by LC/MSMS
• Bisphenol-A in urine by LC/MSMS
• Caffeine and its metabolites in urine
• Calcium in plasma by AA
• Carotenoids including their isomers in plasma by HPLC/PDA (luteins, zeaxanthins, alpha- and beta-cryptoxanthins, lycopenes, alpha- and beta-carotenes)
  
• Cholesterol (total) in plasma by AA
• Coenzyme Q10 in plasma by HPLC/ECD (oxidized, reduced and total Q10)
• Creatinine in urine by AA
• CRP in plasma by AA
• DNA by HPLC
• DNA methylation, global (5-methyl-dC/dG)
• Fatty acids in plasma or RBC's by high-accuracy LCMS (myristic acid [MA, C14:0], stearic acid [SA, C18:0], palmitic acid [PA, C16:0], oleic acid [OA, C18:1], palmitoleic acid [PLA, C16:1], docosapentaenoic acid [DPA, C22:5 n-3], docosahexaenoic acid [DHA, C22:6 n-3], eicosapentaenoic acid [EPA, C20:5 n-3], Î±-linolenic acid [ALA, C18:3 n-3], eicosadienoic acid [EDA, C20:2 n-6], linoleic acid [LA, C18:2 n-6], arachidonic acid [AA, C20:4 n-6], Î±-eleostearic acid [αESA, C18:3]; stearic acid-d3 [SA-d3], linoleic acid-d4 [LA-d4], arachidonic acid-d8 [AA-d8], palmitoleic acid-d14 [PLA-d14], Eicosapentaenoic acid-d5 [EPA-d5], docosahexaenoic acid-d5 [DHA-d5], or any other fatty acid)
• Folates in plasma by LC/MSMS
• Haptoglobin in plasma by AA
• HDL-cholesterol in plasma by AA
• Homocysteine, cysteine in plasma by LCMS
• Isoflavonoids, flavonoids, lignans, anthocyanins or other groups of phenolic agents from plasma, urine, breast milk, foods by LC/MSMS
• Lipid panel in plasma by AA (Chol, HDLC, triglycerides)
• Lipid-Phase Micronutrients in plasma or foods by HPLC/PDA/FD (12 carotenoids, 2 retinoids, 3 tocopherols)
• Metabolomics by LCMS
• Methylmalonic acid in plasma by LC/MSMS
• Nitrogen, urea in urine by AA
• Phthalates in urine by LC/MSMS (phthalate, monoethyl phthalate, mono-n-butyl phthalate, mono-isobutyl phthalate, monobenzyl phthalate, mono(2-ethylhexyl) phthalate, mono(2-ethyl-5-hydroxyhexyl) phthalate, mono(2-ethyl-5-oxohexyl) phthalate, mono(2-ethyl-5-carboxypentyl) phthalate)
• Red blood cell preparation
• Total phenol levels in food, urine, plasma
• Triglycerides in plasma by AA**
• Vitamin A and pro-vitamin A in plasma by HPLC/PDA
• Vitamin B group in plasma by LC/MS (pyridoxic acid, pyridoxal phosphate; folate, 5-methyltetrahydrofolate; methylmalonic acid; homocysteine, cysteine; choline, betaine)
• Vitamin C in plasma, food by HPLC/ECD or PDA
• Vitamin D in plasma by LC/MSMS (vitamin D2, vitamin D3, 25-hydroxy-vitamin D2, and 25-hydroxy-vitamin D3)
• Vitamin E in plasma by NP-HPLC/PDA/FD (all tocopherols)
• Vitamin K by LC/MSMS
• Vitamin and antioxidant panel (lipid soluble) from plasma by single HPLC/PDA/FD (25-hydroxy-vitamin D2 and 25-hydroxy-vitamin D3; alpha-, beta-, gamma-, and delta-tocopherol; all-trans and geometric isomers of lutein, zeaxanthin, alpha- and beta-cryptoxanthin, lycopene, and alpha- and beta-carotene; retinol and retinyl palmitate; ubiquinol-10 and ubiquinone-10)
• Steroids in urine and plasma/serum by LC/MS (estriol [E3], 16-epiestriol [16epi-E3], 17-epiestriol [17epi-E3], 16-ketoestradiol [16keto-E2], 16-α-hydroxyestrone [16αOH-E1], 2-methoxyestrone [2MeO-E1], 3-methoxyestrone [3Me-OE1], 4-methoxyestrone [4MeO-E1], 2-methoxyestradiol [2MeO-E2], 4-methoxyestradiol [4MeO-E2], 2-hydroxyestrone [2OH-E1], 4-hydroxyestrone [4OH-E1], 2-hydroxyestradiol [2OH-E2], progesterone [P], testosterone [T]), corticoids (cortisol, cortisone, etc.) and other steroids
• Any other assay based on clinical autoanalyzer technique (Cobas MiraPlus CC)

Enzyme immunoassays

• 25 Hydroxy Vitamin D
• Adiponectin
• Interleukin-2
• Interleukin-6
• Interleuken-6 soluble Receptor
• Leptin
• Parathyroid Hormone
• TNF alpha
• TNF alpha Receptor I
• TNF alpha Receptor II
• Urinary Isoprostane
• Any other ELISA based assay
• Any Luminex based ELISA assay

Equipment use

• HPLC/PDA systems (no supplies)
• LC/MS system (no supplies)

Consultation

• technical (staff)
• professional (director)
• lab experiments (total analysis including supplies)

All plasma assays can be done from serum.
All other ELISA assays can be performed upon request. Please contact Dr. Franke, This e-mail address is being protected from spambots. You need JavaScript enabled to view it. .

AA = clinical chemistry auto analyzer (Cobas MiraPlus CC)
ECD = electrochemical detection
FD = fluorescence detectionHPLC = high pressure liquid chromatography
HPLC = high pressure liquid chromatography
LC/MS = liquid chromatography mass spectrometry
LC/MSMS = liquid chromatography tandem mass spectrometry
NP = normal-phase
PDA = photo diode array detection
RBC = red blood cells

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If you have any questions about the services offered or a custom designed chemical analysis, please contact Dr. Adrian Franke, PhD at This e-mail address is being protected from spambots. You need JavaScript enabled to view it. .

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