Yuanyuan Fu, PhD
Full Member, Cancer Biology Program, Translational and Clinical Research, University of Hawaiʻi Cancer Center
Academic Appointment(s):
Assistant Professor, University of Hawaiʻi at Mānoa
Graduate Faculty, University of Hawaiʻi at Mānoa
Degree(s):
PhD, Molecular Biosciences and Bioengineering, University of Hawaiʻi at Mānoa
Fellowship(s):
American Association of Cancer Research (2022-2024)
Honor(s)
2025 – AACR Scholar-in-Training Award, American Association for Cancer Research
2024 – The NIH Pathway to Independence Award (K99/R00), National Institutes of Health
2021 – AACR Early Career Investigator Scholarship, American Association for Cancer Research
2019 – Tung and Rachel Liang Endowed Scholarship, University of Hawaiʻi at Mānoa
2017 – Tung and Rachel Liang Endowed Scholarship, University of Hawaiʻi at Mānoa
Research Focus
Genomic and translational bioinformatics; Cancer early detection and etiology, AI/ML in precision oncology.
Selected Publications
Chen Y, Gao Z, Mohd-Ibrahim I, Yang H, Wu L, Fu Y*, Deng Y. Pan-cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumours. Clin Transl Med. 2024 Feb;14(2):e1543. doi: 10.1002/ctm2.1543. PMID: 38303608; PMCID: PMC10835192. (*co-corresponding author)
Fu Y, Wu K, Wang Z, Yang H, Chen Y, Wu L, Yanagihara R, Hedges JR, Wang H, Deng Y. Effectiveness of various COVID-19 vaccine regimens among 10.4 million patients from the National COVID Cohort Collaborative during Pre-Delta to Omicron periods - United States, 11 December 2020 to 30 June 2022. Vaccine. 2023 Oct 6;41(42):6339-6349. doi: 10.1016/j. Vaccine. 2023.08.069. Epub 2023 Sep 22. PubMed PMID: 37741761.
Fu Y, Hu L, Ren HW, Zuo Y, Chen S, Zhang QS, Shao C, Ma Y, Wu L, Hao JJ, Wang CZ, Wang Z, Yanagihara R, Deng Y. Prognostic Factors for COVID-19 Hospitalized Patients with Preexisting Type 2 Diabetes. Int J Endocrinol. 2022 Jan 17; 2022:9322332. doi: 10.1155/2022/9322332. PMID: 35047039; PMCID: PMC8763039.
Fu Y, Katsaros D, Biglia N, Wang Z, Pagano I, Tius M, Tiirikainen M, Rosser C, Yang H, Yu H. Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/β-catenin pathway and associates with favorable prognosis of ovarian cancer. Sci Rep. 2021 Apr 5;11(1):7484. doi: 10.1038/s41598-021-86923-7. PMID: 33820921; PMCID: PMC8021562.
Fu Y, Ling Z, Arabnia H, Deng Y. Current trend and development in bioinformatics research. BMC Bioinformatics. 2020 Dec 3;21:538. doi: 10.1186/s12859-020-03874-y. PMID: 33272214; PMCID: PMC7713158.
Publication list via PubMed
Active Grants
Yuanyuan Fu (contact PI)
NIH’s AIM-AHEAD – Program for Artificial Intelligence Readiness
OT2OD032581-PAIRC2-SUB00450
“Leveraging Multimodal AI/ML for Health Research: Advancing Colorectal Cancer Solutions Through Genomic and Socio-Clinical Integration”
05/01/2025 – 04/30/2027
Yuanyuan Fu (PI)
NIH/NIMHD
K99MD019294
“Identifying unique biological factors as potential targets to mitigate colorectal cancer health disparities”
06/27/2024 – 04/30/2026
Yuanyuan Fu (contact PI)
NIH/RCMI-CC Clinical Research
RCC-004UHI-Pilot
"Deciphering exosomal circulating ncRNA signature for lung cancer early detection and functional networks regulating glutamine metabolism"
08/01/2024 – 04/30/2026
Yuanyuan Fu (subaward PI)
NIH’s AIM-AHEAD – AI/ML in Biomedical Research and Clinical Practice program
1OT2OD032581-02-824
“Exploring circulating ncRNA signature for breast cancer early detection and functional networks regulating BCAAs metabolism”
10/01/2024 – 09/30/2025
Yuanyuan Fu (PI)
American Association for Cancer Research
22-40-68-FU
“Targeting colorectal cancer disparity in Native Hawaiians/Pacific Islanders”
07/1/2022 – 06/30/2024
