Ian Pagano, PhD

Ian Pagano, PhD

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Associate Member, Population Sciences in the Pacific Program (Cancer Prevention in the Pacific), University of Hawaiʻi Cancer Center

Academic Appointment(s):
Assistant Specialist (Assistant Professor), University of Hawaiʻi Cancer Center, University of Hawaiʻi at Mānoa

PhD, MA, Quantitative Psychology, University of Hawaiʻi at Mānoa

Research Focus

I am a biostatistician for the Population Sciences in the Pacific Program and also a member of the Biostatistics Shared Resource. Although I work primarily with the Population Sciences faculty, I provide statistical support to all Cancer Center programs. As part of my specialist position, I write statistical methods for grant applications and manuscripts, manage data, and run analyses. My expertise includes general linear models, logistic regression, factor analysis, structural equation modeling, multilevel models, item response theory, measurement models, dynamical systems, time-to-event (survival) analysis, nonlinear models, construct validation, quality control, sampling, power analysis, and experimental design. I have worked on animal model, clinical trial, and population-based studies investigating the etiology, treatment, and prevention of cancer. These have included the study of disparities in cancer incidence and survival using environment, behavioral, and genetic risk factors.

Selected Publications

Williams RJ, Wills TA, Choi K, Pagano I. Associations for subgroups of E-cigarette, cigarette, and cannabis use with asthma in a population sample of California adolescents. Addict Behav. 2023 Oct;145:107777. doi: 10.1016/j.addbeh.2023.107777. Epub 2023 Jun 12. PubMed PMID: 37336095; PubMed Central PMCID: PMC10330693.

Suarez JS, Novelli F, Goto K, Ehara M, Steele M, Kim JH, Zolondick AA, Xue J, Xu R, Saito M, Pastorino S, Minaai M, Takanishi Y, Emi M, Pagano I, Wakeham A, Berger T, Pass HI, Gaudino G, Mak TW, Carbone M, Yang H. HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2307999120. doi: 10.1073/pnas.2307999120. Epub 2023 Sep 20. PubMed PMID: 37729199; PubMed Central PMCID: PMC10523480.

Bansil S, Silva A, Taniguchi A, Wiedmer C, Fernandez M, Pagano I, Vierkoetter K, Killeen J, Fukui J. Racial/Ethnic Differences Among Tumor-Infiltrating Lymphocytes in Breast Cancer Tumors. Oncologist. 2023 Feb 8;28(2):116-122. doi: 10.1093/oncolo/oyac239. Review. PubMed PMID: 36495151; PubMed Central PMCID: PMC9907033.

Murakami K, Furuya H, Hokutan K, Goodison S, Pagano I, Chen R, Shen CH, Chan MWY, Ng CF, Kobayashi T, Ogawa O, Miyake M, Thornquist M, Shimizu Y, Hayashi K, Wang Z, Yu H, Rosser CJ. Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer. Int J Mol Sci.2023 Mar 3;24(5). doi: 10.3390/ijms24054943. PubMed PMID: 36902377; PubMed Central PMCID: PMC10003630.

Tofaeono V, Tong K, Sy A, Cassel K, Pagano I, Ka'opua LSI, Scanlan L, Thompson L, Vaofanua T, McCutchan JB, Tofaeono V. Validation of the Short-Test of Functional Health Literacy in Adults for the Samoan Population. Health Lit Res Pract. 2022 Oct;6(4):e247-e256. doi: 10.3928/24748307-20220920-01. Epub 2022 Oct 6. PubMed PMID: 36215110; PubMed Central PMCID: PMC9545820.

Publication list via NIH MyBibliography

Active Grants

I. Pagano, Biostatistician; P. Pokhrel, PI
R01 DA053766
"Ethnic Differences in the Effects of COVID-19 on the Substance Use Behavior of Young Adults"
01/2022 – 11/2024

I. Pagano, Biostatistician; S. Okamoto, PI
R01 DA054215
"The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth"
08/2022 – 07/2027

I. Pagano, Biostatistician; Tofaeono, V. and Galvin, J., MPI
RF1 AG075904
"Alzheimer's Disease and Related Dementias (ADRD) Prevalence in American Samoa"
09/2022 – 08/2025

I. Pagano, Biostatistician; C. Rosser, PI
UH3 CA271377
"Application of a Multiplexed Immunoassay for the Detection of Bladder Cancer"
06/2022 – 05/2025