Yurii B. Shvetsov, PhD

Yurii B. Shvetsov, PhD

This email address is being protected from spambots. You need JavaScript enabled to view it. | (808) 564-5825

Full Member, Population Sciences in the Pacific Program (Cancer Epidemiology), University of Hawaiʻi Cancer Center

Academic Appointment(s):
Associate Professor (Associate Researcher), University of Hawaiʻi Cancer Center, University of Hawaiʻi at Mānoa

PhD (Mathematics), Montana State University
MS (Statistics), Montana State University

Research Focus

Dr. Shvetsov’s research focuses on statistical and methodological aspects of cancer epidemiology and on the interplay between infection and cancer. His research interests include validation and improvement of risk prediction models for the most common cancer sites. Many such models were developed using data from homogeneous populations such as Whites. Validating them for non-white populations and improving their predictive performance with the inclusion of additional risk factors is of high scientific and clinical importance. The Multiethnic Cohort, based in Hawaiʻi and Los Angeles (PIs: Le Marchand, Wilkens, Haiman) is a great resource to validate and improve cancer risk prediction models across different races and ethnicities.

Dr. Shvetsov’s other research interest is in elucidating and addressing racial and ethnic disparities in cancer-associated sepsis. In particular, Native Hawaiians exhibit higher rates of sepsis-related mortality than other ethnicities. Uncovering genetic and molecular mechanisms for such disparities could potentially lead to better treatment options for racial and ethnic groups prone to higher risk of sepsis.

Dr. Shvetsov is also interested in methodological questions such as developing and implementing composite measures of exposure, in particular for dietary and neighborhood factors; parametric and nonparametric methods of assessing nonlinear functional form of a relationship between factors of interest, and reliability of laboratory measurements and its effect on the analysis and interpretation of data from epidemiologic studies. As a member of the Biostatistics Shared Resource, he also works on studies led by other UH Cancer Center researchers, offering his expertise in study design, methodology and data analysis.

Selected Publications

Shvetsov YB, Wilkens LR, White KK, Chong M, Buyum A, Badowski G, Leon Guerrero RT, Novotny R. (2022). Prediction of breast cancer risk among women of the Mariana Islands: the BRISK retrospective case-control study. BMJ Open. Dec 9;12(12):e061205. PubMed Central PMCID: PMC9743286.

Shvetsov YB, Ogino MH, Glibetic N, Asato CB, Wilkens LR, Le Marchand L, Matter ML. (2021). Association of sepsis mortality with specific cancer sites and treatment type: The Multiethnic Cohort Study. J Pers Med; Feb 19;11(2) PubMed Central PMCID: PMC7922684.

Shvetsov YB, Shariff-Marco S, Yang J, Conroy SM, Canchola AJ, Albright CL, Park SY, Monroe KR, Le Marchand L, Gomez SL, Wilkens LR, Cheng I. (2020). Association of change in the neighborhood obesogenic environment with colorectal cancer risk: The Multiethnic Cohort Study. SSM Popul Health; Apr;10:100532. PubMed Central PMCID: PMC6940713.

Shvetsov YB, Harmon BE, Ettienne R, Wilkens LR, Le Marchand L, Kolonel LN, Boushey CJ. (2016). The influence of energy standardisation on the alternate Mediterranean diet score and its association with mortality in the Multiethnic Cohort. Br J Nutr; Nov;116(9):1592-1601. PubMed Central PMCID: PMC5505740.

Shvetsov YB, Song MA, Cai Q, Tiirikainen M, Xiang YB, Shu XO, Yu H. (2015). Intraindividual variation and short-term temporal trend in DNA methylation of human blood. Cancer Epidemiol Biomarkers Prev; Mar;24(3):490-7. PubMed Central PMCID: PMC4355238.

Publication list via PubMed