Experimental Design and Power Calculations – We highly encourage you to consult our bioinformaticians prior to experiments to find a solution that fits your needs and budget. We will help design your experiments to obtain maximum leverage and perform data quality control checks for high-throughput data projects.

Liaison with vendors: We will help identify the right product to ensure the quality of your research.

Next Generation Sequence Analysis

1. Assembly and gene annotation
2. DNA-Seq
3. RNA-Seq including fusion gene and LncRNA
4. Small RNA-Seq
5. Chip-Seq
6. Target-Seq
7. Meth-Seq
8. Single cell sequencing
9. Metagenomics

Microarray data analysis

1. Gene expression
2. NanoString
3. Exon array for alternative splicing
4. SNP array, GWAS
5. miRNA array
6. DNA methylation array
7. CNV

Proteomics data and Protein array

1. Protein mass-spec data for protein expression and interaction
2. Phosphor-screen
3. Glycol-screen
4. PTM (post translational modification) Profiling

Metabolomics data analysis

1. Lipidomics
2. Sugar profiling
3. Entire metabolomics data analysis

Multivariate biomarker identification and classification

1. Feature selection algorithms
2. Classification algorithms
3. Artificial intelligence and building machine learning models

Gene pattern, function analysis, systems biology

1. Gene and sample correlation and clustering analysis
2. Gene enrichment analysis
3. Gene ontology and pathway analysis
4. Gene network analysis
5. Integrative "omics" data analysis

Image data analysis

We will provide hardware and software support for UH researchers who plan to conduct preliminary data analysis for hypothesis development and testing as part of grant proposal writing. We will provide necessary guidance to include computational biological methods to analyze data in your research analysis plan. Letters of support for your grant proposal can be prepared upon request.

We will provide data management services and develop a web-based database for collection, storage, integration, and management of clinical data and scientific research data.

We are involved in collaborative research of several principal investigators from different UH departments and campuses. We perform bioinformatics data analysis by running routine bioinformatics applications and custom programs developed specifically to fulfill our research objectives.